These started with a joke I heard back when Independence Day came out. Supposedly during the scene where the Brett Spiner character is getting thrashed by the alien in the exoskeleton, in some theatre somewhere, a small boy piped up "In real life, Data would kick the alien's butt."
I started collecting more 'in real life' sayings, where reality gets a littly blurry. Here are two I remember, and will add more as I come across them.
During the aftermath of Hurricane Katrina, the governor went on TV and pathetically cried, begging the federal government for assistance. In real life, if Laura Roslin was governor, she would have organized and led her own convoy into New Orleans, twenty four hours ahead of FEMA.
While watching Star Wars: Attack of the Clones, I felt a moment of liking for Anakin Skywalker when he insisted they investigate the attempted assasination of Padma. But then I realized, in real life, Lord Auditor Vorkosigan would have unmasked Palpatine in about three days, cutting out the need for a third movie.